Estimation of C-reactive Protein and Total Serum Immunoglobulin Concentrations after Uterine Immunomodulation in Repeat Breeding Cows

Twenty one repeat breeding cows were screened for subclinical endometritis and they were assigned equally to one control group and two treatmentgroups. Cows in the control group were infused with 50 ml of normal saline intra-uterine. Out of the two treatment groups, cows in group I were treated with 20 ml of colostrum as intra uterine medication. Cows in treatment group II were infused with 10 ml of non pathogenic E.coli (pure attenuated culture obtained from Himedia Product code – ATCC 25922). C-reactive protein concentrations and total immunoglobulin concentrations were calculated on day 0, day 7th, day 14th and day 21st of estrus cycle from the blood sample. The estimation of C-reactive protein in all the experimental groups revealed a range between1.2 – 4.8 mg/dl with the negative values obtained for 21 day of estimation indicating improvement of uterine health. Comparison of immunoglobulin values for different days in all the treatment protocol revealed a significant (p<0.05) difference within various days of sampling.